Investigation Epidemiological and Immunological Variable (IL-6) Resulting from Infection with Hydatid Cysts in Al-Najaf Hospitals: Case Control Study

Abstract

Background: Human echinococcosis is a zoonotic disease caused by a species of medical importance, the Echinococcus granulosus, an etiological agent of cystic echinococcosis (CE) .  

 Material and methods: A radiological examination will be performed for these patients to diagnose Echinococcus granulosus parasite by find echinococcal cysts. All of these patients were involved  in this study and   during the period   starting from October 2023 to the end of January 2024, from all ages of patient from both sex (Males and Females  At Al-Sader Medical City, AL-Hakeem General Hospital, AL-Haidarya general Hospital and Al-Hayat Hospital.

Results: The mean level of IL-6 in patients is 181.22 pg/ml, which is significantly higher than the mean level of 25.7 pg/ml in controls (p-value < 0.001). This suggests that patients have elevated IL-6 levels compared to healthy individuals.

Conclusion: The prevalence of hydatid disease in Al-Najaf Al-Ashraf in this study was 33%. There is evidence that individual differences in cytokine (Interleukin-6)  levels may affect development or susceptibility to disease.